Medication-Induced Sexual Dysfunction

Sexual dysfunction can be a side effect of several medications. Often, people are unaware of these effects when they begin taking the medications, making them even more troubling.

Post-SSRI Sexual Dysfunction (PSSD)

Selective serotonin reuptake inhibitors (SSRIs) are prescribed for depression, anxiety and other mental health disorders and can have severe sexual side effects, known as post-SSRI sexual dysfunction (PSSD).

Symptoms of PSSD may include:

  • Erectile dysfunction
  • Reduced sensation in genitals
  • Delayed orgasm or inability to orgasm (anorgasmia)
  • Muted orgasms or lack of pleasure with orgasm
  • Decreased libido (sex drive)
  • Decreased or absent nocturnal erections
  • Premature ejaculation

Diagnostic workup may include:

  • Comprehensive medical history including current and previous medications
  • Detailed physical exam
  • Blood tests
  • Penile ultrasound with Doppler technology to look for structural abnormalities, abnormal blood flow, scar tissue, or penile curvature.

Once a diagnosis is established, we created a customize treatment plan with each patient.

This may include:

  • Behavioral Treatment Strategies / Sex Therapy
  • Specialized physical therapy
  • Medications
  • Additional testing

Post-Finasteride Syndrome (PFS)

Men who have taken finasteride or other 5-alpha reductase inhibitors for enlarged prostate or androgenic alopecia (male pattern baldness) may develop distressing sexual and non-sexual complaints, known as post-finasteride syndrome.

Symptoms of PFS may include:

  • Decreased libido
  • Erectile dysfunction
  • Penile shrinkage
  • Orgasmic anhedonia (loss of pleasure with orgasm)
  • Fatigue
  • Muscle atrophy
  • Depression
  • Brain fog
  • Difficulty sleeping

Other Conditions Treated

If you would like to schedule an appointment to speak with Dr. Rubin, please call us at 202-293-1000.