Medication-Induced Sexual Dysfunction

Sexual dysfunction can be a side effect of several medications. Often, people are unaware of these effects when they begin taking the medications, making them even more troubling.

Post-SSRI Sexual Dysfunction (PSSD)

Selective serotonin reuptake inhibitors (SSRIs) are prescribed for depression, anxiety and other mental health disorders and can have severe sexual side effects, known as post-SSRI sexual dysfunction (PSSD).

Symptoms of PSSD may include:

• Erectile dysfunction
• Reduced sensation in genitals
• Delayed orgasm or inability to orgasm (anorgasmia)
• Muted orgasms or lack of pleasure with orgasm
• Decreased libido (sex drive)
• Decreased or absent nocturnal erections
• Premature ejaculation

Diagnostic workup may include:

• Comprehensive medical history including current and previous medications
• Detailed physical exam
• Blood tests
• Penile ultrasound with Doppler technology to look for structural abnormalities, abnormal blood flow, scar tissue, or penile curvature.

Once a diagnosis is established, we created a customize treatment plan with each patient.

This may include:

• Behavioral Treatment Strategies / Sex Therapy
• Specialized physical therapy
• Medications
• Additional testing

Post-Finasteride Syndrome (PFS)

Men who have taken finasteride or other 5-alpha reductase inhibitors for enlarged prostate or androgenic alopecia (male pattern baldness) may develop distressing sexual and non-sexual complaints, known as post-finasteride syndrome.

Symptoms of PFS may include:

• Decreased libido
• Erectile dysfunction
• Penile shrinkage
• Orgasmic anhedonia (loss of pleasure with orgasm)
• Fatigue
• Muscle atrophy
• Depression
• Brain fog
• Difficulty sleeping